Clinical trial registry record

Effects of Vitamin B3 Derivative Nicotinamide Riboside (NR) in Bone, Skeletal Muscle and Metabolic Functions in Aging

A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.

Plain-language guide

Five questions to ask about this record

What this is
A clinical study registration, not a result or recommendation.
Why it may matter
The registry currently reports Completed.
Evidence
Registered phase not reported study.
Main limitation
Registration does not prove that the intervention works, is safe, or is available to you.
What changed
Registry metadata was last updated February 26, 2025.
Where to verify
Open the primary registry below for eligibility, locations, contacts, and current status.
Registry ID
NCT03818802
Last registry update
February 26, 2025
Status
Completed
Phase
Phase not reported
Sponsor
Mayo Clinic
Enrollment
53
Countries
United States
Match confidence
100%
Source feed
ClinicalTrials.gov
Automated source synopsis

A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.

Evidence snapshot

What the source actually supports

Evidence stage
Phase not reported
Study design
RANDOMIZED · PARALLEL · PREVENTION · DOUBLE
Evidence population
Human clinical study registration
Participants
53
Population
FEMALE · 65 Years to 80 Years
Duration
2019-09-16 to 2024-11-08
Intervention
Nicotinamide Riboside; Placebo
Comparator
Nicotinamide Riboside; Placebo
Outcomes measured
Maximal oxygen uptake (VO2 max) test — 6 months; Skeletal muscle function — 6 months; Short Physical Performance Battery (SPPB) — 6 months; Respiration rate on muscle biopsy samples — 6 months; PCR on muscle biopsy samples — 6 months; Immunoblot on muscle biopsy samples — 6 months; Bone metabolism — 6 months; Glucose profile — 6 months; Insulin — 6 months; Lipid profile — 6 months; Hemoglobin A1C — 6 months; Oral glucose tolerance test — 6 months
Reported result
No reusable finding-level result is available in this record.

Main limitationThis is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.

Safety and approvalEligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians. Trial registration is not regulatory approval and does not establish that an intervention is available.

Source supportStructured registry protocol metadata; no finding-level conclusion is generated.

Trial stage · Phase not reportedA trial phase describes development stage; it does not establish a positive result.
Phase 1Phase 2Phase 3Phase 4

Registration and recruitment status do not establish safety, efficacy, or regulatory approval.

Why this record appears here · 100% topic match

The title, summary, or source keywords matched one or more topics followed by immortal.life. A higher percentage means a stronger topic match; it does not rate safety, effectiveness, or study quality.

  • NAD metabolism · 100%Title contains controlled term: nicotinamide riboside. Abstract contains controlled term: nicotinamide riboside. Source terminology contains: nicotinamide riboside. Title supplies longevity context: aging. Study type is explicitly identified as INTERVENTIONAL.

Automated source check 100% · update recency 65%. These figures help sort records; they are not medical ratings.

nad metabolism
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