Clinical trial registry record

Deciphering the Effect of Moderate Wine Consumption on Healthy Aging Through Postprandial Extracellular Vesicles.

A registered study indexed because it matched monitored longevity research terms. Registry status: Recruiting. Registration does not establish safety or effectiveness.

Plain-language guide

Five questions to ask about this record

What this is
A clinical study registration, not a result or recommendation.
Why it may matter
The registry currently reports Recruiting.
Evidence
Registered phase not reported study.
Main limitation
Registration does not prove that the intervention works, is safe, or is available to you.
What changed
Registry metadata was last updated January 23, 2026.
Where to verify
Open the primary registry below for eligibility, locations, contacts, and current status.
Registry ID
NCT07361887
Last registry update
January 23, 2026
Status
Recruiting
Phase
Phase not reported
Sponsor
University of Seville
Enrollment
8
Countries
Spain
Match confidence
100%
Source feed
ClinicalTrials.gov
Automated source synopsis

A registered study indexed because it matched monitored longevity research terms. Registry status: Recruiting. Registration does not establish safety or effectiveness.

Evidence snapshot

What the source actually supports

Evidence stage
Phase not reported
Study design
RANDOMIZED · CROSSOVER · BASIC SCIENCE · SINGLE
Evidence population
Human clinical study registration
Participants
8
Population
ALL · 35 Years to 36 Years
Duration
2025-11-01 to 2027-03-31
Intervention
White Wine; Red Wine; Water
Comparator
Water (Control)
Outcomes measured
Concentration of circulating extracellular vesicles — Baseline (0 hours), postprandial peak (2 hours after beverage int…; Mean size of circulating extracellular vesicles — Baseline (0 hours), postprandial peak (2 hours after beverage intake)…; Postprandial changes in extracellular vesicle proteome — Baseline (0 hours), postprandial peak (2 hours after beverage…; Postprandial changes in extracellular vesicle lipidome — Baseline (0 hours), postprandial peak (2 hours after beverage…; Change from baseline in plasma glucose concentration — Baseline (0 hours), 2 hours, and 6 hours after beverage intake; Change from baseline in plasma insulin concentration — Baseline (0 hours), 2 hours, and 6 hours after beverage intake; Change from baseline in plasma triglyceride concentration — Baseline (0 hours), 2 hours, and 6 hours after beverage int…; Change from baseline in plasma total cholesterol concentration — Baseline (0 hours), 2 hours, and 6 hours after beverag…; Change from baseline in plasma HDL cholesterol concentration — Baseline (0 hours), 2 hours, and 6 hours after beverage…; Change from baseline in plasma LDL cholesterol concentration — Baseline (0 hours), 2 hours, and 6 hours after beverage…; Change from baseline in plasma interleukin-6 (IL-6) concentration — Baseline (0 hours), 2 hours, and 6 hours after beve…; Change from baseline in plasma tumor necrosis factor alpha (TNF-α) concentration — Baseline (0 hours), 2 hours, and 6 h…; Change from baseline in plasma interleukin-1 beta (IL-1β) concentration — Baseline (0 hours), 2 hours, and 6 hours afte…; Change from baseline in plasma monocyte chemoattractant protein-1 (MCP-1/CCL2) concentration — Baseline (0 hours), 2 ho…; Transendothelial electrical resistance (TEER) in an in vitro human blood-brain barrier model after exposure to postpran…; Claudin-5 (CLDN5) protein expression in an in vitro human blood-brain barrier model after exposure to postprandial extr…; Occludin (OCLN) protein expression in an in vitro human blood-brain barrier model after exposure to postprandial extrac…; Interleukin-6 (IL-6) concentration in microglial culture supernatant after exposure to postprandial extracellular vesic…; Tumor necrosis factor alpha (TNF-α) concentration in microglial culture supernatant after exposure to postprandial extr…; IL1B mRNA expression in microglia after exposure to postprandial extracellular vesicles — EVs isolated at baseline (0 h…
Reported result
No reusable finding-level result is available in this record.

Main limitationThis is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.

Safety and approvalEligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians. Trial registration is not regulatory approval and does not establish that an intervention is available.

Source supportStructured registry protocol metadata; no finding-level conclusion is generated.

Trial stage · Phase not reportedA trial phase describes development stage; it does not establish a positive result.
Phase 1Phase 2Phase 3Phase 4

Registration and recruitment status do not establish safety, efficacy, or regulatory approval.

Why this record appears here · 100% topic match

The title, summary, or source keywords matched one or more topics followed by immortal.life. A higher percentage means a stronger topic match; it does not rate safety, effectiveness, or study quality.

  • Intercellular communication · 100%Title contains controlled term: extracellular vesicle. Abstract contains controlled term: extracellular vesicle. Title supplies longevity context: aging. Study type is explicitly identified as INTERVENTIONAL.

Automated source check 100% · update recency 85%. These figures help sort records; they are not medical ratings.

intercellular communication
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