Clinical trial registry record

Effect of Topical Sulforaphane on Skin Aging and With Ultraviolet and Visible Light Exposure

A registered EARLY_PHASE1 study indexed because it matched monitored longevity research terms. Registry status: Active Not Recruiting. Registration does not establish safety or effectiveness.

Plain-language guide

Five questions to ask about this record

What this is
A clinical study registration, not a result or recommendation.
Why it may matter
The registry currently reports Active Not Recruiting.
Evidence
Registered early phase 1 study.
Main limitation
Registration does not prove that the intervention works, is safe, or is available to you.
What changed
Registry metadata was last updated September 4, 2026.
Where to verify
Open the primary registry below for eligibility, locations, contacts, and current status.
Registry ID
NCT03730649
Last registry update
September 4, 2026
Status
Active Not Recruiting
Phase
EARLY Phase 1
Sponsor
Johns Hopkins University
Enrollment
12
Countries
United States
Match confidence
100%
Source feed
ClinicalTrials.gov
Automated source synopsis

A registered EARLY_PHASE1 study indexed because it matched monitored longevity research terms. Registry status: Active Not Recruiting. Registration does not establish safety or effectiveness.

Evidence snapshot

What the source actually supports

Evidence stage
EARLY Phase 1
Study design
NON RANDOMIZED · PARALLEL · PREVENTION · NONE
Evidence population
Human clinical study registration
Participants
12
Population
ALL · 18 Years
Duration
2019-10-09 to 2027-10-01
Intervention
Sulforaphane (broccoli sprout extract); UV or visible light
Comparator
Sulforaphane without light challenge; Sulforaphane with light challenge
Outcomes measured
keratin 16 presence as determined by immunofluorescence assay — Up to 6 months; keratin 17 presence as determined by immunofluorescence assay — Up to 6 months; keratin 16 fold change as determined by Reverse Transcription Polymerase Chain Reaction (RT-PCR) — Up to 6 months; keratin 17 fold change as determined by RT-PCR — Up to 6 months; keratin expression changes as determined by RT-PCR — Up to 6 months
Reported result
No reusable finding-level result is available in this record.

Main limitationThis is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.

Safety and approvalEligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians. Trial registration is not regulatory approval and does not establish that an intervention is available.

Source supportStructured registry protocol metadata; no finding-level conclusion is generated.

Trial stage · EARLY Phase 1A trial phase describes development stage; it does not establish a positive result.
Phase 1Phase 2Phase 3Phase 4

Registration and recruitment status do not establish safety, efficacy, or regulatory approval.

Why this record appears here · 100% topic match

The title, summary, or source keywords matched one or more topics followed by immortal.life. A higher percentage means a stronger topic match; it does not rate safety, effectiveness, or study quality.

  • Skin ageing · 100%Title contains controlled term: skin aging. Abstract contains controlled term: skin aging. Source terminology contains: skin aging. Title supplies longevity context: aging. Study type is explicitly identified as INTERVENTIONAL.

Automated source check 100% · update recency 100%. These figures help sort records; they are not medical ratings.

skin aging
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