Clinical trial registry record

Noradrenergic Dysregulation, Sleep and Cognition in Older Adults With Insomnia

A registered study indexed because it matched monitored longevity research terms. Registry status: Recruiting. Registration does not establish safety or effectiveness.

Plain-language guide

Five questions to ask about this record

What this is
A clinical study registration, not a result or recommendation.
Why it may matter
The registry currently reports Recruiting.
Evidence
Registered phase not reported study.
Main limitation
Registration does not prove that the intervention works, is safe, or is available to you.
What changed
Registry metadata was last updated March 30, 2026.
Where to verify
Open the primary registry below for eligibility, locations, contacts, and current status.
Registry ID
NCT06694441
Last registry update
March 30, 2026
Status
Recruiting
Phase
Phase not reported
Sponsor
Northwestern University
Enrollment
60
Countries
United States
Match confidence
100%
Source feed
ClinicalTrials.gov
Automated source synopsis

A registered study indexed because it matched monitored longevity research terms. Registry status: Recruiting. Registration does not establish safety or effectiveness.

Evidence snapshot

What the source actually supports

Evidence stage
Phase not reported
Study design
RANDOMIZED · PARALLEL · TREATMENT · SINGLE
Evidence population
Human clinical study registration
Participants
60
Population
ALL · 55 Years
Duration
2024-09-30 to 2029-08-31
Intervention
Light Exposure; Placebo
Comparator
Dim Red Light
Outcomes measured
24h plasma norepinephrine — Enrollment to the end of treatment at 10 weeks.; Clonidine suppression test — Enrollment; Wake after sleep onset (WASO) — Enrollment to the end of treatment at 10 weeks.; Slow oscillatory activity during sleep — Enrollment to the end of treatment at 10 weeks.; Pittsburg Sleep Quality Index — Enrollment to the end of treatment at 10 weeks.; NIH tool box — Enrollment to the end of treatment at 10 weeks.; 24-h plasma 3-methoxy-4-hydroxyphenylglycol (MHPG) — Enrollment to the end of treatment at 10 weeks.; 24-h plasma cortisol levels — Enrollment to the end of treatment at 10 weeks.; 24h plasma melatonin — Enrollment to the end of treatment at 10 weeks.; Pupillometry — Enrollment to the end of treatment at 10 weeks.; Psychomotor Vigilance Test — Enrollment to the end of treatment at 10 weeks.; Wake EEG — Enrollment to the end of treatment at 10 weeks.; Heart Rate and Heart Rate Variability — Enrollment to the end of treatment at 10 weeks.; Insomnia Severity Index — Enrollment to the end of treatment at 10 weeks.; Visual Analogue Scale — Enrollment to the end of treatment at 10 weeks.
Reported result
No reusable finding-level result is available in this record.

Main limitationThis is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.

Safety and approvalEligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians. Trial registration is not regulatory approval and does not establish that an intervention is available.

Source supportStructured registry protocol metadata; no finding-level conclusion is generated.

Trial stage · Phase not reportedA trial phase describes development stage; it does not establish a positive result.
Phase 1Phase 2Phase 3Phase 4

Registration and recruitment status do not establish safety, efficacy, or regulatory approval.

Why this record appears here · 100% topic match

The title, summary, or source keywords matched one or more topics followed by immortal.life. A higher percentage means a stronger topic match; it does not rate safety, effectiveness, or study quality.

  • Sleep · 100%Title contains controlled term: sleep. Abstract contains controlled term: sleep. Title supplies longevity context: older adult. Study type is explicitly identified as INTERVENTIONAL.

Automated source check 100% · update recency 100%. These figures help sort records; they are not medical ratings.