Clinical trial registry record

Sleep and Healthy Aging Research on Depression for Younger Women

A registered PHASE1 study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.

Plain-language guide

Five questions to ask about this record

What this is
A clinical study registration, not a result or recommendation.
Why it may matter
The registry currently reports Completed.
Evidence
Registered phase 1 study.
Main limitation
Registration does not prove that the intervention works, is safe, or is available to you.
What changed
Registry metadata was last updated January 27, 2026.
Where to verify
Open the primary registry below for eligibility, locations, contacts, and current status.
Registry ID
NCT03848715
Last registry update
January 27, 2026
Status
Completed
Phase
Phase 1
Sponsor
University of California, Los Angeles
Enrollment
40
Countries
United States
Match confidence
80%
Source feed
ClinicalTrials.gov
Automated source synopsis

A registered PHASE1 study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.

Evidence snapshot

What the source actually supports

Evidence stage
Phase 1
Study design
RANDOMIZED · PARALLEL · OTHER · TRIPLE
Evidence population
Human clinical study registration
Participants
40
Population
FEMALE · 25 Years to 44 Years
Duration
2019-10-02 to 2024-07-22
Intervention
Endotoxin; Placebo
Comparator
Placebo
Outcomes measured
Non-social (Monetary) Reward Response (Reward Learning and Sensitivity) — Baseline and post-injection (2.25 hrs); Non-social (Monetary) Reward Response (Reward Motivation) — Baseline and post-injection (2.1 hrs); Non-social (Monetary) Reward Response (Reward Sensitivity) — Baseline and post-injection (2.1 hrs); General Social Reward Response (Reward Sensitivity Via Emotional Dot Probe) — Baseline and post-injection (2.7 hrs); General Social Reward Response (Reward Sensitivity Via Face Morphing Task) — Baseline and post-injection (2.8 hrs); General Social Reward Response (Social Reward Motivation) — Baseline and post-injection (2 hrs); Depressed Mood Subscale of the Profile of Mood States (POMS) — Hourly, from pre-injection (T0) to 9 hours later (T9); Close Social Reward Response — Post-injection (2.9 hrs); Consummatory Daily Reward Response — 14 days (7 days pre-injection; 7 days post-injection).; Dopaminergic Activity — Baseline and post-injection (1.9 hrs); Anticipatory Daily Reward Response — 14 days (7 days pre-injection; 7 days post-injection).
Reported result
No reusable finding-level result is available in this record.

Main limitationThis is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.

Safety and approvalEligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians. Trial registration is not regulatory approval and does not establish that an intervention is available.

Source supportStructured registry protocol metadata; no finding-level conclusion is generated.

Trial stage · Phase 1A trial phase describes development stage; it does not establish a positive result.
Phase 1Phase 2Phase 3Phase 4

Registration and recruitment status do not establish safety, efficacy, or regulatory approval.

Why this record appears here · 80% topic match

The title, summary, or source keywords matched one or more topics followed by immortal.life. A higher percentage means a stronger topic match; it does not rate safety, effectiveness, or study quality.

  • Sleep · 80%Title contains controlled term: sleep. Title supplies longevity context: aging. Study type is explicitly identified as INTERVENTIONAL.

Automated source check 100% · update recency 85%. These figures help sort records; they are not medical ratings.