A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.
What the source actually supports
- Evidence stage
- Phase not reported
- Study design
- RANDOMIZED · FACTORIAL · PREVENTION · SINGLE
- Evidence population
- Human clinical study registration
- Participants
- 406
- Population
- ALL · 65 Years to 79 Years
- Duration
- 2008-04-01 to 2010-12-01
- Intervention
- Exercise and nutritional integrated care; Usual care with education; Problem solving therapy (PST) integrated care
- Comparator
- UC group
- Outcomes measured
- improvement of frailty — baseline, 3, 6, and 12 months; Bone Mineral Density — baseline and 12 months; quality of life assessment — pilot study: baseline, 3, 6, and 12 months, 2009 study: baseline, 6, and 12 months; QUALEFFO_31 — pilot study: baseline, 3, 6, and 12 months, 2009 study: baseline, 6, and 12 months; barthel index — pilot study: baseline, 3, 6, and 12 months, 2009 study: baseline and 12 months; PRIME-MD (only measured in pilot study) — baseline, 3, 6, and 12 months; BDI-II (only measured in 2009 study) — baseline, 6, and 12 months; health-resource utilization — pilot study: baseline, 3, 6, and 12 months, 2009 study: baseline, 6, and 12 months; Original Frailty Indicators — baseline, 3, 6, and 12 months; timed up and go — baseline, 3, 6, and 12 months; one leg stand time — baseline, 3, 6, and 12 months; dominant hand grip strength — baseline, 3, 6, and 12 months; dominant knee extension power — baseline, 3, 6, and 12 months; vitamin B12 in blood — pilot study: baseline and 12 month, 2009 study: baseline and 6 months; vitamin D in blood — pilot study: baseline and 12 month, 2009 study: baseline and 6 months; CRP in blood — pilot study: baseline and 12 month, 2009 study: baseline and 6 months; testosterone in blood — pilot study: baseline and 12 month, 2009 study: baseline and 6 months; IL-6 in blood — pilot study: baseline and 12 month, 2009 study: baseline and 6 months
- Reported result
- No reusable finding-level result is available in this record.
Main limitationThis is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.
Safety and approvalEligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians. Trial registration is not regulatory approval and does not establish that an intervention is available.
Source supportStructured registry protocol metadata; no finding-level conclusion is generated.
Registration and recruitment status do not establish safety, efficacy, or regulatory approval.
Why this record appears here · 100% topic match
The title, summary, or source keywords matched one or more topics followed by immortal.life. A higher percentage means a stronger topic match; it does not rate safety, effectiveness, or study quality.
- Bone ageing · 100%Title contains controlled term: osteoporosis. Abstract contains controlled term: osteoporosis. Source terminology contains: osteoporosis. Title supplies longevity context: frailty, frail. Study type is explicitly identified as INTERVENTIONAL.
Automated source check 100% · update recency 35%. These figures help sort records; they are not medical ratings.