Clinical trial registry record

Dark Adaptation as an Early Indicator of Response to Statin Therapy for Intermediate AMD

A registered PHASE2 study indexed because it matched monitored longevity research terms. Registry status: Recruiting. Registration does not establish safety or effectiveness.

Plain-language guide

Five questions to ask about this record

What this is
A clinical study registration, not a result or recommendation.
Why it may matter
The registry currently reports Recruiting.
Evidence
Registered phase 2 study.
Main limitation
Registration does not prove that the intervention works, is safe, or is available to you.
What changed
Registry metadata was last updated January 26, 2026.
Where to verify
Open the primary registry below for eligibility, locations, contacts, and current status.
Registry ID
NCT04735263
Last registry update
January 26, 2026
Status
Recruiting
Phase
Phase 2
Sponsor
Massachusetts Eye and Ear Infirmary
Enrollment
21
Countries
United States
Match confidence
60%
Source feed
ClinicalTrials.gov
Automated source synopsis

A registered PHASE2 study indexed because it matched monitored longevity research terms. Registry status: Recruiting. Registration does not establish safety or effectiveness.

Evidence snapshot

What the source actually supports

Evidence stage
Phase 2
Study design
NA · SINGLE GROUP · TREATMENT · NONE
Evidence population
Human clinical study registration
Participants
21
Population
ALL · 50 Years to 85 Years
Duration
2021-02-04 to 2028-01-01
Intervention
Atorvastatin 80mg
Comparator
Not reported
Outcomes measured
Change in Dark Adaptation recovery time measured by change in Rod Intercept time (RIT) — 18 Months; Change in drusen volume measured by Spectral Domain OCT — 18 months; To correlate visual functions of dark adaption with change in drusen volume — 18 months; To correlate Best Corrected Visual Acuity and retinal structural evaluation of study patients — 18 months; To correlate change in contrast sensitivity and retinal structural evaluation of study patients — 18 months; To correlate change in microperimetry visual functional and retinal structural evaluation of study patients — 18 months
Reported result
No reusable finding-level result is available in this record.

Main limitationThis is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.

Safety and approvalEligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians. Trial registration is not regulatory approval and does not establish that an intervention is available.

Source supportStructured registry protocol metadata; no finding-level conclusion is generated.

Trial stage · Phase 2A trial phase describes development stage; it does not establish a positive result.
Phase 1Phase 2Phase 3Phase 4

Registration and recruitment status do not establish safety, efficacy, or regulatory approval.

Why this record appears here · 60% topic match

The title, summary, or source keywords matched one or more topics followed by immortal.life. A higher percentage means a stronger topic match; it does not rate safety, effectiveness, or study quality.

  • Vision ageing · 60%Source terminology contains: age-related macular degeneration. Source terminology supplies longevity context: age-related. Study type is explicitly identified as INTERVENTIONAL.

Automated source check 100% · update recency 85%. These figures help sort records; they are not medical ratings.

vision aging
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