Clinical trial registry record

Assessment of the effect of geroprotectors on how cells work in the human body

A registered Phase II study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.

Plain-language guide

Five questions to ask about this record

What this is
A clinical study registration, not a result or recommendation.
Why it may matter
The registry currently reports Completed.
Evidence
Registered phase ii study.
Main limitation
Registration does not prove that the intervention works, is safe, or is available to you.
What changed
Registry metadata was last updated June 22, 2026.
Where to verify
Open the primary registry below for eligibility, locations, contacts, and current status.
Registry ID
ISRCTN47919839
Last registry update
June 22, 2026
Status
Completed
Phase
Phase II
Sponsor
University of Birmingham
Enrollment
0
Countries
United Kingdom, England
Match confidence
100%
Source feed
ISRCTN Registry
Automated source synopsis

A registered Phase II study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.

Evidence snapshot

What the source actually supports

Evidence stage
Phase II
Study design
Interventional
Evidence population
Human clinical study registration
Participants
0
Population
All · Senior
Duration
2024-11-01 to 2026-06-30
Intervention
Metformin MR, fisetin, spermidine; Drug
Comparator
Not reported
Outcomes measured
Number of senescent cells in adipose tissue measured by the SA-β-GAL technique after 3 weeks of intervention, adjusted…; 1. Senescent cell burden in adipose tissue as measured by transcriptomics using SenMayo analysis after 3 weeks of inter…
Reported result
No reusable finding-level result is available in this record.

Main limitationThis is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.

Safety and approvalEligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians. Trial registration is not regulatory approval and does not establish that an intervention is available.

Source supportStructured registry protocol metadata; no finding-level conclusion is generated.

Trial stage · Phase IIA trial phase describes development stage; it does not establish a positive result.
Phase 1Phase 2Phase 3Phase 4

Registration and recruitment status do not establish safety, efficacy, or regulatory approval.

Why this record appears here · 100% topic match

The title, summary, or source keywords matched one or more topics followed by immortal.life. A higher percentage means a stronger topic match; it does not rate safety, effectiveness, or study quality.

  • Metformin · 100%Abstract contains controlled term: metformin. Source terminology contains: metformin. Source terminology supplies longevity context: ageing. Study type is explicitly identified as Interventional.

Automated source check 98% · update recency 100%. These figures help sort records; they are not medical ratings.

metformin
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