A registered PHASE1 study indexed because it matched monitored longevity research terms. Registry status: Withdrawn. Registration does not establish safety or effectiveness.
What the source actually supports
- Evidence stage
- Phase 1
- Study design
- RANDOMIZED · FACTORIAL · TREATMENT · TRIPLE
- Evidence population
- Human clinical study registration
- Participants
- 0
- Population
- ALL · 50 Years
- Duration
- 2023-01-31 to 2023-01-31
- Intervention
- Experimental: Computerized Cognitive Training; Experimental: Open-label antidepressant treatment; Active Comparator: Solitaire Training; Placebo Comparator: Placebo-controlled antidepressant treatment
- Comparator
- Solitaire Training; Placebo-controlled antidepressant treatment
- Outcomes measured
- Hamilton Rating Scale for Depression (HRSD) Change — Screen, Weeks 0, 1, 2, 3, 4, 6, 8, 10, 12; Treatment Credibility Expectancy Scale (CES) - item 4 Change — Baseline, Week 0; Processing Speed Change - WAIS-IV Coding — Baseline, Weeks 4, 12; Processing Speed Change - NIHH Toolbox Pattern Comparison Processing Speed Test — Baseline, Weeks 4, 12; Processing Speed Change - Trail Making Test A — Baseline, Weeks 4, 12; Resting State Functional Connectivity Index Change — Baseline, Week 4; Secondary Clinical Global Impressions (CGI) Severity and Improvement — Screen, Weeks 0, 1, 2, 3, 4, 6, 8, 10, 12; Inventory for Depressive Symptomatology Self-Report (IDS-SR) — Weeks 0, 1, 2, 3, 4, 6, 8, 10, 12; Cumulative Illness Rating Scale for Geriatrics (CIRS-G) — Screen; NIH Toolbox Auditory Verbal Learning Test - Rey (RAVLT) — Baseline, Weeks 4, 12; Stroop Color-Word Test (Stroop) — Measure of response inhibition sensitive to frontal lobe dysfunction. This test is di…; Letter and Animal Naming Test — Baseline, Weeks 4, 12; World Health Organization Disability Assessment Schedule 2.0 (WHODAS2.0) — Screen, Weeks 4, 6, 8, 10, 12; Trail Making Test A and B — Baseline, Weeks 4, 12; NIH Toolbox Flanker Inhibitory Control and Attention Test — Baseline, Weeks 4, 12; NIH Toolbox Picture Sequence Memory Test — Baseline, Weeks 4, 12; NIH Toolbox List Sorting Working Memory Test — Baseline, Weeks 4, 12; NIH Toolbox Picture Vocabulary Test — Baseline, Weeks 4, 12; NIH Toolbox Oral Reading Recognition Test — Baseline, Weeks 4, 12; NIH Toolbox Dimensional Card Change Sort Test — Baseline, Weeks 4, 12
- Reported result
- No reusable finding-level result is available in this record.
Main limitationThis is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.
Safety and approvalEligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians. Trial registration is not regulatory approval and does not establish that an intervention is available.
Source supportStructured registry protocol metadata; no finding-level conclusion is generated.
Registration and recruitment status do not establish safety, efficacy, or regulatory approval.
Why this record appears here · 100% topic match
The title, summary, or source keywords matched one or more topics followed by immortal.life. A higher percentage means a stronger topic match; it does not rate safety, effectiveness, or study quality.
- Cognitive training · 100%Title contains controlled topic terminology. Summary contains controlled topic terminology. Source terminology contains a controlled topic term. Title supplies ageing or longevity context.
Automated source check 100% · update recency 50%. These figures help sort records; they are not medical ratings.