Clinical trial registry record

Subretinal Macugen® for Neovascular Age-Related Macular Degeneration

A registered PHASE3 study indexed because it matched monitored longevity research terms. Registry status: Unknown. Registration does not establish safety or effectiveness.

Plain-language guide

Five questions to ask about this record

What this is
A clinical study registration, not a result or recommendation.
Why it may matter
The registry currently reports Unknown.
Evidence
Registered phase 3 study.
Main limitation
Registration does not prove that the intervention works, is safe, or is available to you.
What changed
Registry metadata was last updated September 27, 2011.
Where to verify
Open the primary registry below for eligibility, locations, contacts, and current status.
Registry ID
NCT00788177
Last registry update
September 27, 2011
Status
Unknown
Phase
Phase 3
Sponsor
Klinikum Ludwigshafen
Enrollment
10
Countries
Germany
Match confidence
100%
Source feed
ClinicalTrials.gov
Automated source synopsis

A registered PHASE3 study indexed because it matched monitored longevity research terms. Registry status: Unknown. Registration does not establish safety or effectiveness.

Evidence snapshot

What the source actually supports

Evidence stage
Phase 3
Study design
NON RANDOMIZED · SINGLE GROUP · TREATMENT · NONE
Evidence population
Human clinical study registration
Participants
10
Population
ALL · 50 Years
Duration
2008-11-01 to 2012-12-01
Intervention
Pegaptanib (Macugen®)
Comparator
Not reported
Outcomes measured
Proportion of patients who had lost fewer than 15 letters of visual acuity at 54 weeks — 54 weeks; Mean change from baseline in total size of lesion and total size of CNV at 12, 24 and 54 weeks — week 24 and 54; Changes in best corrected visual acuity (BCVA) from baseline at 54 weeks — 54 weeks; Mean change from baseline in at week 12 and 24 — week 12 and 24; Proportion of patients who gain ≥ 5, 10, 15 letters of BCVA from baseline at week 24 and 54 — week 24 and 54; Proportion of patients who lose less than 15 letters of BCVA from baseline at week 24 and 54 — week 24 and 54; Change in area of leakage at 12, 24 and 54 weeks — weeks 12, 24 and 54; Mean change in retinal thickness by OCT at center of fovea at 12, 24 and 54 weeks — weeks 12, 24 and 54
Reported result
No reusable finding-level result is available in this record.

Main limitationThis is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.

Safety and approvalEligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians. Trial registration is not regulatory approval and does not establish that an intervention is available.

Source supportStructured registry protocol metadata; no finding-level conclusion is generated.

Trial stage · Phase 3A trial phase describes development stage; it does not establish a positive result.
Phase 1Phase 2Phase 3Phase 4

Registration and recruitment status do not establish safety, efficacy, or regulatory approval.

Why this record appears here · 100% topic match

The title, summary, or source keywords matched one or more topics followed by immortal.life. A higher percentage means a stronger topic match; it does not rate safety, effectiveness, or study quality.

  • Vision ageing · 100%Title contains controlled topic terminology. Summary contains controlled topic terminology. Source terminology contains a controlled topic term. Title supplies ageing or longevity context.

Automated source check 100% · update recency 35%. These figures help sort records; they are not medical ratings.