Clinical trial registry record

L-citrulline and Metformin in Duchenne's Muscular Dystrophy

A registered PHASE3 study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.

Plain-language guide

Five questions to ask about this record

What this is
A clinical study registration, not a result or recommendation.
Why it may matter
The registry currently reports Completed.
Evidence
Registered phase 3 study.
Main limitation
Registration does not prove that the intervention works, is safe, or is available to you.
What changed
Registry metadata was last updated April 19, 2018.
Where to verify
Open the primary registry below for eligibility, locations, contacts, and current status.
Registry ID
NCT01995032
Last registry update
April 19, 2018
Status
Completed
Phase
Phase 3
Sponsor
University Hospital, Basel, Switzerland
Enrollment
47
Countries
Switzerland
Match confidence
100%
Source feed
ClinicalTrials.gov
Automated source synopsis

A registered PHASE3 study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.

Evidence snapshot

What the source actually supports

Evidence stage
Phase 3
Study design
RANDOMIZED · PARALLEL · TREATMENT · QUADRUPLE
Evidence population
Human clinical study registration
Participants
47
Population
ALL · 78 Months to 10 Years
Duration
2013-10-01 to 2016-03-01
Intervention
750 mg metformin and 7.5 g L-citrulline daily p.o.; Placebo
Comparator
Placebo
Outcomes measured
Mean change of motor function measure (MFM) D1 subscore (assessing standing and transfers) — baseline to week 26; Mean change of MFM total score, the D2, and D3 MFM subscores — baseline to week 26; Mean change of six minute walking distance (6MWD) — baseline to week 26; Change of quantitative muscle MRI (Magnetic Resonance Imaging) including muscle fat content (MFC) and T2 times of thigh…; Change in the plasma/urine concentration for markers of muscle necrosis, oxidative stress, nitrosative stress, and chan…; Mean change of quantitative muscle force (QMT) of knee extension and elbow flexion using hand held dynamometry (HHD) —…
Reported result
No reusable finding-level result is available in this record.

Main limitationThis is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.

Safety and approvalEligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians. Trial registration is not regulatory approval and does not establish that an intervention is available.

Source supportStructured registry protocol metadata; no finding-level conclusion is generated.

Trial stage · Phase 3A trial phase describes development stage; it does not establish a positive result.
Phase 1Phase 2Phase 3Phase 4

Registration and recruitment status do not establish safety, efficacy, or regulatory approval.

Why this record appears here · 100% topic match

The title, summary, or source keywords matched one or more topics followed by immortal.life. A higher percentage means a stronger topic match; it does not rate safety, effectiveness, or study quality.

  • Metformin · 100%Title contains controlled topic terminology. Summary contains controlled topic terminology. Source terminology contains a controlled topic term.

Automated source check 100% · update recency 50%. These figures help sort records; they are not medical ratings.

metformin
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